The complex hexaploid wheat genome offers many challenges for genomics research. Expressed sequence tags facilitate the analysis of gene-coding regions and provide a rich source of molecular markers for mapping and comparison with model organisms. The objectives of this study were to construct a high-density EST chromosome bin map of wheat homoeologous group 2 chromosomes to determine the distribution of ESTs, construct a consensus map of group 2 ESTs, investigate synteny, examine patterns of duplication, and assess the colinearity with rice (...) of ESTs assigned to the group 2 consensus bin map. A total of 2600 loci generated from 1110 ESTs were mapped to group 2 chromosomes by Southern hybridization onto wheat aneuploid chromosome and deletion stocks. A consensus map was constructed of 552 ESTs mapping to more than one group 2 chromosome. Regions of high gene density in distal bins and low gene density in proximal bins were found. Two interstitial gene-rich islands flanked by relatively gene-poor regions on both the short and long arms and having good synteny with rice were discovered. The map locations of two ESTs indicated the possible presence of a small pericentric inversion on chromosome 2B. Wheat chromosome group 2 was shown to share syntenous blocks with rice chromosomes 4 and 7. (shrink)

En el presente artículo se evidencia la vinculación que establece Rama entre lengua/literatura y espacio/poder en La ciudad letrada. Este nuevo paradigma ha permitido pensar y repensar la literatura latinoamericana y los estudios culturales, sin embargo, entraña contradicciones dentro del mismo pensamiento del uruguayo. La tajante división que el autor establece entre ciudad real y ciudad letrada hace imposible pensar el rol de la literatura fuera de la esfera del poder institucional, al mismo tiempo que relega ontológicamente la realidad de (...) esta última a una meramente instrumental. Nuestra propuesta es leer a la luz del concepto de transculturación esta oposición, para establecer una dialéctica que permita considerar la politicidad propia de la ciudad real y su rol activo en la expresión de una literatura de resistencia política. (shrink)

Resumen: En el presente artículo se evidencia la vinculación que establece Rama entre lengua/literatura y espacio/poder en La ciudad letrada. Este nuevo paradigma ha permitido pensar y repensar la literatura latinoamericana y los estudios culturales, sin embargo, entraña contradicciones dentro del mismo pensamiento del uruguayo. La tajante división que el autor establece entre ciudad real y ciudad letrada hace imposible pensar el rol de la literatura fuera de la esfera del poder institucional, al mismo tiempo que relega ontológicamente la realidad (...) de esta última a una meramente instrumental. Nuestra propuesta es leer a la luz del concepto de transculturación esta oposición, para establecer una dialéctica que permita considerar la politicidad propia de la ciudad real y su rol activo en la expresión de una literatura de resistencia política. Abstract: In the present article we show the relationship that Rama establish between language/power and space/power in the Ciudad Letrada. This new paradigm has allowed us to think and rethink Latin American literature and cultural studies, non the less, it also brings out contradictions inside the own thinking of the Uruguayan author. The strong division that the author establishes between the real city and the literate city does not allow one to think of the role of literature outside the field of institutionalized power, at the same time that he relegates the ontological reality of the latter to a merely instrumental one. Our proposal is to read this opposition in the light of the notion of transculturation, establishing a dialectic that allows us to consider the very policy of the real city and its active role in the expression of a political resistance literature. (shrink)

Cell division is an universal process the aim of which is the equitable distribution of subcellular organelles from single cells to their daughters. The extraordinary accuracy with which the genetic material is partitioned requires a complex machinery involving many gene products. Genetic approaches can be used to identify the relevant components and processes, and mutational analysis of loci essential for cell division has been carried out in several eukaryotes, in particular fungi and mammalian cells in culture. Recently, this type of (...) analysis has been extended to Drosophila, an ideal eukaryote for genetic studies. We will review here the genetic dissection of mitosis in Drosophila melanogaster, discussing recent findings of interest and the methodological problems that have been encountered. (shrink)

Análisis y revisión historiográfica actualizada de los distintos periodos constructivos de la Giralda: islámico, medieval, renacentista, barroco y de los siglos XIX y XX. En todos ellos se insiste en las personalidades y mentalidades que influyeron en su fisonomía. Se concluye con una revisión de las diferentes artes plásticas: Arquitectura, Escultura, Pintura, Mobiliario, Orfebrería. Bordados, Estampación, Arte Popular, y recreaciones e interpretaciones de la torre en las que se ejemplifican los distintos tipos y usos del monumento sevillano.

AI systems are bringing an augmentation of human capabilities to shape the world. They may also drag a replacement of human conscience in large chunks of life. AI systems can be designed to leave moral control in human hands, to obstruct or diminish that moral control, or even to prevent it, replacing human morality with pre-packaged or developed ‘solutions’ by the ‘intelligent’ machine itself. Artificial Intelligent systems (AIS) are increasingly being used in multiple applications and receiving more attention from the (...) public and private organisations. The purpose of this article is to offer a mapping of the technological architectures that support AIS, under the specific focus of the moral agency. Through a literature research and reflection process, the following areas are covered: a brief introduction and review of the literature on the topic of moral agency; an analysis using the BDI logic model (Bratman 1987); an elemental review of artificial ‘reasoning’ architectures in AIS; the influence of the data input and the data quality; AI systems’ positioning in decision support and decision making scenarios; and finally, some conclusions are offered about regarding the potential loss of moral control by humans due to AIS. This article contributes to the field of Ethics and Artificial Intelligence by providing a discussion for developers and researchers to understand how and under what circumstances the ‘human subject’ may, totally or partially, lose moral control and ownership over AI technologies. The topic is relevant because AIS often are not single machines but complex networks of machines that feed information and decisions into each other and to human operators. The detailed traceability of input-process-output at each node of the network is essential for it to remain within the field of moral agency. Moral agency is then at the basis of our system of legal responsibility, and social approval is unlikely to be obtained for entrusting important functions to complex systems under which no moral agency can be identified. (shrink)

Research on the effects of particularistic human resource practices (i.e., favoritism and nepotism) on organizational outcomes has concentrated on direct negative attitudinal and behavioral responses. By integrating legitimacy and social exchange theories, this paper proposes and tests the idea that legitimacy of particularistic practices might moderate their negative effects on employee attitudes at work. Through a survey of 415 employees across multiple organizational types, we show that the legitimacy of particularism mitigates its negative effects on affective commitment and perceived distributive (...) and procedural justice in non-family-owned businesses only. We discuss implications for theory and practice. (shrink)

This paper takes a phenomenological perspective regarding the difficulties encountered in daily life by man in prehistory. I argue that the economics of beingnecessarily establishes man as a being that must make choices. Of these, man must eventually arrive at the realization that higher, rather than lower choices will safeguard human survival, well being and allow for prosperity. The economics of being is a form of identifying economic choice-making as a natural disposition of man’s. It is the latter condition that (...) makes man act in the world. However, even though man must act, action cannot be blind. Instead, human action is motivated and guided by man’s sense of interiority. That is, man’s existential capacity for self-reflection is also what can deliver us to autonomous rule. This form of reflective choice-making is a creative act. The paper attempts to trace this aspect of the human condition back to prehistory, in order to demonstrate that societies, institutions, invention, technology, artistic creation and economic responsibility come about as the result of human industriousness. None of the aforementioned are creations of modern man. (shrink)

Montague’s theory of language is used to present a formal system that can be impIemented directly using PROLOG to obtain a semantic interpreter capable of analysing an im portant fragment of the Spanish language.

Number processing abilities are important for academic and personal development. The course of initial specialization of ventral occipito-temporal cortex sensitivity to visual number processing is crucial for the acquisition of numeric and arithmetic skills. We examined the visual N1, the electrophysiological correlate of vOTC activation across five time points in kindergarten, middle and end of first grade, second grade, and fifth grade. A combination of cross-sectional and longitudinal EEG data of a total of 62 children at varying familial risk for (...) dyslexia were available to form groups of 23, 22, 27, 27, and 42 participants for each of the five time points. The children performed a target detection task which included visual presentation of single digits, false fonts, and letters to derive measures for coarse and fine digit sensitive processing across development. The N1 amplitude analyses indicated coarse and fine sensitivity characterized by a stronger N1 to digits than false fonts across all five time points, and stronger N1 to digits than letters at all but the second time point. In addition, lower arithmetic skills were associated with stronger coarse N1 digit sensitivity over the left hemisphere in second grade, possibly reflecting allocation of more attentional resources or stronger reliance on the verbal system in children with poorer arithmetic skills. To summarize, our results show persistent visual N1 sensitivity to digits that is already present early on in pre-school and remains stable until fifth grade. This pattern of digit sensitivity development clearly differs from the relatively sharp rise and fall of the visual N1 sensitivity to words or letters between kindergarten and middle of elementary school and suggests unique developmental trajectories for visual processing of written characters that are relevant to numeracy and literacy. (shrink)

In this article, the dominant legitimating discursive strategies around the ever-increasing labour demands and ever-declining standards of safety and well-being at work in Spain are analysed through the lens of Boltanski and Thévenot’s (2006) view of the transformation of capitalism. A qualitative methodology based on semi-structured interviews is used. Results show that the justificatory arguments most commonly put forward by managers and experts are the logic of supply and demand, and values related to flexibility, resilience and adaptability to change. In (...) contrast, the stability and protection established in the twentieth century are widely cherished values, particularly among union representatives and some human resources specialists. We found that discourse practices map two specific legitimating categories (market values and a projects orientation), and one critical category (Civic World), but the critical category has no practical impact, as the predominant feeling is resignation. Our research describes the common attitudes to legitimacy in the job market and points to a deep discontent in some of its key agents. (shrink)

COMUNIDADES DE DIALOGO E INDAGACION, PARA EXPERIENCIAS AGROECOLOGICAS EN EDUCACION INTERCULTURAL / CommunitIes of Dialogue and Inquiry, for agroecological experiences about intercultural education La Comunidad de indagación, practicada como herramienta para facilitar diálogos interculturales en el ámbito de la AgroEcología, en combinación con el “Método de Campesino a Campesino”. Propuestas metodológicas de la Filosofía con niñez y adolescencia, adaptadas a espacios educativos en zonas rurales atendiendo colectivos de diversas generaciones. Compartiremos experiencias acerca de Sistematización y Evaluación de proyectos educativos, con (...) énfasis en interculturalidad, relacionadas a la praxis de la agroecología, soberanía alimentaria y sustentabilidad. Entre Chiapas, México, del año 2001 al 2016; Huehuetenango, Guatemala, de 2009 a 2016, y una estancia como docente voluntario en el Instituto de Agroecología LatinoAmericana "IALA María Cano" en Cundinamarca, Colombia, en la primavera de 2017. Con el objetivo de compartir propuestas para otros espacios de construcción colectiva de saberes. -/- Community of Inquiry, practiced as a facilitation tool for intercultural dialogues in the environment of Agroecology, combined with the Method of “Campesino a Campesino”. Proposals from Philosophy for Children and Teenagers, adapted to rural education spaces attending to collectives of diverse ages. We´ll share experiences about systematization, and evaluating education projects with an intercultural emphasis, related with the praxis of agroecology, food sovereignity and sustainability. Between Chiapas, México, from the years 2001 to 2016; Huehuetenango, Guatemala, from 2009 to 2016, and a teaching volunteer stay during the spring of 2017 at the Institute of Agroecology for LatinAmerica “IALA María Cano” of Cundinamarca, Colombia. Aiming to share proposals for other spaces of collective construction of knowledges. (shrink)

Trait emotional intelligence concerns our perceptions of our emotional abilities, that is, how good we believe we are in terms of understanding, regulating, and expressing emotions in order to adapt to our environment and maintain well-being. In this article, we present succinct summaries of selected findings from research on the location of trait EI in personality factor space, the biological underpinnings of the construct, indicative applications in the areas of clinical, health, social, educational, organizational, and developmental psychology, and trait EI (...) training. Findings to date suggest that individual differences in trait EI are a consistent predictor of human behavior across the life span. (shrink)

El presente trabajo plantea la necesidad de volver a la clásica distinción de conocimiento teórico y conocimiento práctico y repensar el lugar de la voluntad y la libertad humanas en el proceso cognoscitivo en general. Desde la consideración de la noción de conciencia, del valor dado a la dimensión cognoscitiva en el ámbito moral, la índole del conocer como relación con lo real y la idea de verdad, llegamos a la conclusión de que el planteamiento racionalista que excluye a la (...) fe como ajena al conocimiento lo hace por el mismo motivo por el que excluye a la voluntad: para evitar la necesidad de tener que decidir. (shrink)

Traditionally, liberals have confined religion to the sphere of the ‘private’ or ‘non-political’. However, recent debates over the place of religious symbols in public spaces, state financing of faith schools, and tax relief for religious organisations suggest that this distinction is not particularly useful in easing the tension between liberal commitments to equality on the one hand, and freedom of religion on the other. This article deals with one aspect of this debate, which concerns whether members of religious communities should (...) receive exemptions from regulations that place a distinctively heavy burden on them. Drawing on Habermas’ understanding of churches as ‘communities of interpretation’, we explore possible alternatives to both the ‘rule-and-exemption’ approach and the ‘neutralist’ approach. Our proposal rests on the idea of mutual learning between secular and religious perspectives. On this interpretation, what is required is (i) the generation and maintenance of public spaces in which there could be discussion and dialogue about particular cases, and (ii) evaluation of whether the basic conditions of moral discourse are present in these spaces. Thus deliberation becomes a touchstone for the building of a shared democratic ethos. (shrink)

ExcerptCzesław Miłosz issues from an age and place when making a distinction between the ethos of a poet, an essayist, or a philosopher seemed an unnecessary and imprudent indiscretion. His resplendent work on political philosophy, The Captive Mind, is along with Albert Camus' The Rebel one of the most insightful, historically accurate, and devastating critiques of Marxism and its entrenchment in twentieth-century thought to date. As such, The Captive Mind is unrivalled by other “theoretical” and abstract treatises in its sheer (...) ability to grasp the vital essence of political reality under totalitarian regimes. As a poet and an essayist, Miłosz's…. (shrink)

José Ortega y Gasset,, Spanish writer, philosopher and revolutionary was noted for his humanistic criticism of modern civilization. His best known work, The Revolt of the Masses earned him an international reputation. In it, he decried the destructive influence of the mass-minded, and therefore mediocre, people, who, if not directed by the intellectually and morally superior minority, encourage the rise of fascism and totalitarianism.

Con ocasión de la edición digital de sus Obras Completas y... nada más.

My dissertation is a critical study of Jose Ortega Y Gasset's attempt to reconcile his notion of lived-experience , which is fundamentally immediate experience, with his idea of life as vital-reason. But life as vital reason is, itself, best understood as consisting of life as a rational-existential project. This, in effect is Ortega's manner of fusing idealism and realism. The result of this mediation is to be interpreted as the self-with-things or what amounts to: I-in-the-world. Man is never what he (...) is in his immediacy and therefore he must create his essence through a self-conscious existential project. Thus, Ortega's notion of life as radical reality is the culmination of an underlying dialectic that is present throughout his work. That is, man's self-awareness of his life as a pre-reflective extranatural phenomenon vis-a-vis the material world can only be understood through reflection and therefore never in its immediacy. Therefore I conclude that for Ortega the synthesis of these apparently antithetical notions culminates in a form of subjective idealism given that primacy is necessarily attributed to the self over the external world. Even though I accept the fundamental tenets of his argument concerning the synthesis of Realism and Idealism and Rationalism and Vitalism, I have focused upon the inherent tension that exists in any such reflective endeavor. I believe that due to Ortega's emphasis that all reflection must originate and therefore concern itself with life as phenomenon, his philosophy necessarily gives primacy to the self over the material world . In arguing "Yo Soy Yo Y Mis Circumstancias" Ortega stresses the character of the Rational Vitalism that results from my self-awareness of my life as a problem for reflection that is forged through my necessary dealings with the world. The result of this self-knowledge is the foundation of a metaphysics of life that is best understood as man as radical reality. (shrink)

Some Lessons in Metaphysics is José Ortega y Gasset’s testament to metaphysics in relation to existential longing. While Ortega writes about metaphysics in other of his works, it is in Some Lessons in Metaphysics that he defines metaphysics as springing from man’s immediate necessity to find coherence in individual human existence, which man experiences as a «shipwrecked» being in the cosmos. Metaphysical reflection aims to establish coherence and meaning in human life. As a result of existential inquietude, Ortega argues that (...) metaphysics is the cornerstone of thoughtful philosophical reflection for people who «need it». (shrink)

According to Ortega, human history comes about as the discovery of differentiated, self-aware life that encounters itself in a reservoir of possibilities. Properly speaking, history does not exist until man, who is a metaphysical/existential entity, becomes aware of responsibility in choice-making. For this reason, human history signifies more than just historical events. Instead, history is the outward manifestation of the trajectory of personal life, either as ensimismamiento or alteración. In Toward a Philosophy of History, Ortega explains history as a vital (...) process that originates in the exuberance of free will. In Ortega’s thought, history is the domain of metaphysical/existential beings, and not the culmination of a “blind” process. Ortega’s philosophy of history locates history-making in the choices of individuals through vital reason. This is what he ultimately means by historical reason.ion, he suggests, revolts against life. (shrink)

Meditations on Hunting is a book that expands José Ortega y Gasset’s philosophy of man as an extra-natural being. Man is extra-natural because, while man has a relationship with his physical circumstance, this is not the only factor that defines man. In Meditations on Hunting Ortega reminds us that a life worth living is a life that is alert to itself. Existential authenticity, then, requires that man sustain a sense of awe and wonder about his own existence and the world (...) that surrounds us. The life-long strain that existential authenticity demands of man, I refer to as existential alertness. This intensity of vital reflection is fueled by a form of reflective perspicuity that never allows human existence to become too comfortable; to the point of acting as a detriment to self-reflection. I believe that existential alertness is an existential category that Ortega’s work illuminates in a way that few thinkers have paid attention to. (shrink)

Philosophical Perspective on Cinema addresses the relationship between human existence and sensual reality. Applying metaphysical/existential reflection to cinema, the author explores the philosophical clarity that cinema can offer reflective persons about the human experience.